Novel Inhibitors for Fungal Glycosidases Based on Cyclohexane-1,2-dicarboxylic Acids
نویسندگان
چکیده
Novel carbasugars derived from cyclohexane-1,2-dicarboxylic acid were synthesized and tested for inhibitory activity towards fungal glycosidases from Aspergillus oryzae and Penicillium canescens. Significant inhibition was observed, which magnitude depended on configuration of substituents.
منابع مشابه
Novel easily accessible glucosidase inhibitors: 4-hydroxy-5-alkoxy-1,2-cyclohexanedicarboxylic acids.
Glycosidases are very important enzymes involved in a variety of biochemical processes with a special importance to biotechnology, food industry, and pharmacology. Novel structurally simple inhibitors derived from cyclohexane-1,2-dicarboxylic acids were synthesized and tested against several fungal glycosidases from Aspergillus oryzae and Penicilliumcanescens. The presence of at least two carbo...
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